Continual infusion of intrathecal baclofen (ITB): long-term effect on spasticity.
نویسندگان
چکیده
BACKGROUND Spasticity is a disorder of muscular function causing muscular tightness or spasm which occurs when there is damage to the central nervous system whether it is of spinal cord or brain origin. This insult could be either pathological or traumatic. METHOD Thirty-three patients had intrathecal Baclofen pumps implanted for severe spasticity. These patients either did not respond to or tolerate oral medications. RESULTS All patients showed significant improvement in their spasms following the procedure. Improvement was noted not only in spasticity, but also in pain, management of sleep disturbance, activities of daily living, indoor and outdoor mobility and behavior. CONCLUSION The number of complications was acceptable, and generally were not life-threatening. Infection was the significant complication in two patients and this led to explantation of their pumps. Patient satisfaction was very high and was related to improvement in the quality of life for the patients.
منابع مشابه
[Intrathecal baclofen therapy for hereditary spastic paraplegia].
Intrathecal baclofen therapy (ITB) is an established treatment for intractable spasticity. More than 1,100 patients have undergone ITB in Japan, and there are about 50 hereditary spastic paraplegia (HSP) The features of ITB in HSP are 1. small doses of baclofen may often be enough, 2. small changes of doses later the symptoms remarkably, 3. doses can be decreased after long term ITB.
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INTRODUCTION Treatment of severe spasticity and dystonia with intrathecal baclofen (ITB) in children has been shown to be effective and has therefore been employed in the Region of Southern Denmark. The aim of this retrospective study was to analyse the efficacy and adverse events since ITB was introduced in 2003. METHODS A total of 46 children who had a baclofen pump from April 2003 to Janua...
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عنوان ژورنال:
- Middle East journal of anaesthesiology
دوره 20 6 شماره
صفحات -
تاریخ انتشار 2010